Biological Mechanisms and Therapeutic Potential of Molecular Hydrogen

This book explores the emerging role of molecular hydrogen (H₂) as a therapeutic agent for managing and preventing non-communicable chronic disorders (NDs). The chapters examine the molecular mechanisms, physiological impact, and applications of molecular hydrogen across a broad spectrum of diseases, including neurodegenerative, metabolic, cardiovascular, and autoimmune disorders. The book presents the role of molecular hydrogen in oxidative stress reduction, inflammation modulation, and cellular protection. It also explores the effects of molecular hydrogen on gut microbiota, radioprotection, and immune modulation. Additionally, it discusses advanced administration methods, pharmacokinetics, pharmacodynamics, and combination therapies to optimize the therapeutic efficacy of molecular hydrogen. It further highlights ongoing trials, future research directions, and translational applications in medicine and healthcare.

Key Features:

• Explores the molecular mechanisms and therapeutic potential of molecular hydrogen in managing neurodegenerative diseases, cancer, cardiovascular diseases, and metabolic disorders
• Examines the role of molecular hydrogen in neuroprotection, focusing on Alzheimer’s and Parkinson’s disease, and its impact on neurodegeneration
• Discusses the effects of molecular hydrogen on cancer cell metabolism, radioprotection, and gut microbiota dysbiosis
• Covers innovative administration techniques, pharmacokinetics, and pharmacodynamics of molecular hydrogen
• Explores synergistic therapeutic approaches, including photochemical activation and combination therapies to enhance bioavailability and efficacy of molecular hydrogen

This book is an important resource for researchers and students of biomedical sciences, pharmaceutical sciences, and biochemistry.