Tackling Antibiotic Resistance

Antibiotic resistance, the so-called silent pandemic, is a serious global health concern that has already cost millions of lives. This book provides strategies for combating antibiotic resistance by presenting in-depth reviews of the nature and seriousness of the issue and discussing strategies and methods to deal with the evolution of resistance. Chapters unlock potential applications of alternative strategies. Comprehensive and updated information is presented for readers, for example, the use of nanomaterials as antimicrobials to cure infections caused by superbugs or the use of artificial intelligence and machine learning for overall control of antibiotic resistance in bacteria. Antibiotic stewardship programs are among the key strategies to control antibiotic resistance in bacteria. A review of an ideal stewardship program is presented. In addition, the promising roles of bacteriophages, antibacterial peptides, CRISPR-Cas systems and aptamers are reviewed in separate chapters with current updates on research and developments, drugs in the pipeline, and future perspectives.