The Adenosinergic System
A Non-Dopaminergic Target in Parkinson’s Disease
Micaela Morelli editor Nicola Simola editor Jadwiga Wardas editor
Format:Paperback
Publisher:Springer International Publishing AG
Published:22nd Oct '16
Should be back in stock very soon
Adenosine A2A receptor antagonists have shown great promise in the treatment of Parkinson's Disease and alleviation of symptoms. This book addresses various aspects of this class of drugs from their chemical development to their clinical use. Among the many insightful chapters contained in this book, there are three unique reviews that have not previously been published in any format: (1) a history of istradefylline, the first A2A antagonist approved for treatment of Parkinson's Disease, (2) an overview of neuroimaging studies in human death and disease and (3) a study of urate as a possible biomarker and neuroprotectant.
“This is an excellent text on the role of adenosine & its metabolites in parkinson’s disease, cerebral ischemia. … The book will benefit neurologists, pharmacologists, researchers, and biochemists with inical interests.” (Joseph J. Grenier, Amazon.com, January, 2017)
“The authors have gathered updated and high-quality chapters from world-leading experts in the field to provide essential information on the development of novel therapies for the treatment of Parkinson’s disease and related neurodegenerative disorders. … The audience is neuroscientists who work at either the preclinical and/or clinical phases of understanding the underlying mechanisms and novel molecular targets related to the cause and treatment of Parkinson’s disease and related neurodegenerative disorders.” (Thomas L. Pazdernik, Doody’s Book Reviews, December, 2015)
ISBN: 9783319371863
Dimensions: unknown
Weight: unknown
337 pages
Softcover Reprint of the Original 1st 2015 ed.