Drug Selectivity
An Evolving Concept in Medicinal Chemistry
Helmut Buschmann editor Raimund Mannhold editor Jörg Holenz editor Norbert Handler editor
Format:Hardback
Publisher:Wiley-VCH Verlag GmbH
Published:10th Jan '18
£153.95
Available to order, but very limited on stock - if we have issues obtaining a copy, we will let you know.
The book "Drug Selectivity - An Evolving Concept in Medicinal Chemistry" provides a current overview and comprehensive compilation for medicinal chemists that discusses the effects of aiming for multiple targets on the entire drug development process.
The result is a broad survey of current and future strategies for drug selectivity in medicinal chemistry with theoretical but also practical aspects. Different strategies are presented and evaluated, such as various design approaches, merged multiple ligands, discovery technologies and a broad range of successful examples of unselective drugs taken from all major disease areas. With its wide-ranging view of an emerging new paradigm in drug development, this handbook is of prime importance for every medicinal and pharmaceutical chemist.
In summary, this is a very good and valuable book for graduate students as well as medicinal chemists in academia and pharmaceutical companies. Readers will find many interesting chapters, some of which are more oriented to experts, while others are well suited for beginners. I recommend this book to those working in the field of medicinal chemistry, or even pharmacology, who have a particular interest in selective and selectively nonselective drugs. (Prof. Antonio Macchiarulo, ChemMedChem 19/2018)
ISBN: 9783527335381
Dimensions: 252mm x 175mm x 28mm
Weight: 1157g
536 pages