Cullin-RING Ligases and Protein Neddylation
Biology and Therapeutics
Yi Sun editor Wenyi Wei editor Jianping Jin editor
Format:Paperback
Publisher:Springer Verlag, Singapore
Published:3rd Jan '21
Currently unavailable, and unfortunately no date known when it will be back
This paperback is available in another edition too:
- Hardback£129.99(9789811510243)

This book summarizes all the important aspects of CRLs (Cullin-RING E3 Ubiquitin Ligases), while providing details of mechanistic specifics that go beyond protein ubiquitination and neddylation. Ubiquitin ligases, including the CRLs, which are activated by neddylation, play an important role in diverse biological processes and are involved in various human diseases, particularly cancer. The book covers various topics, such as CRL structure, biology, genetics, its regulation by neddylation, its pivotal role in human disease, and its potential in drug discovery and targeted therapies. The book appeals to biochemists and biologists working in other fields, and, given the importance of CRLs in all aspects of cell biology and the great promise of targeting these complexes for therapy, is a valuable resource anyone interested in modern biology or medicine.
ISBN: 9789811510274
Dimensions: unknown
Weight: unknown
372 pages
2020 ed.