Physiology, Pharmacology and Clinical Significance of Arachidonic Acid

This book elaborates on arachidonic acid (AA) as a critical component of cell membranes, impacting membrane fluidity. Chapters discuss how higher AA levels in cell membranes enhance receptor expression and their affinity to proteins, hormones, and growth factors. Further, chapters explore the role of AA as the precursor for pro-inflammatory prostaglandins, thromboxanes, leukotrienes, and anti-inflammatory lipoxin A4, influencing inflammation, wound healing, and homeostasis. The book delves into the role of AAin regulating immune responses, impacting macrophages, T cells, NK cells, and anti-cancer actions.

It provides profound insights into AA's diverse physiological and pathological roles and serves as a valuable resource for students, researchers, physicians, scientists, and healthcare workers.