Protein-Protein Interactions

This volume explores the role of protein-protein interactions in diseases like cancer and neurodegenerative disorders, providing insights into drug discovery and therapeutic approaches.

The second volume of Protein-Protein Interactions delves into the critical role of protein-protein interactions (PPIs) in various human diseases. It covers a range of conditions, including cancer, neurodegenerative disorders, immune diseases, and inflammation, highlighting how these interactions contribute to disease mechanisms. The book provides a comprehensive overview of the structural aspects and ligand-based drug design methods that aid in the discovery of small molecules capable of inhibiting PPIs associated with these diseases.

In addition to discussing drug discovery, Protein-Protein Interactions explores a variety of computational and experimental tools that researchers utilize to investigate the anomalous interactions that underlie these diseases. These methodologies are essential for understanding the complexities of PPIs and their implications in pathophysiology. The volume emphasizes the importance of accurate interaction assessment in the development of therapeutic strategies.

Furthermore, the book reviews classical interactions between pathogens and their hosts, shedding light on how these dynamics are responsible for the pathophysiology of infectious diseases. By integrating knowledge from various fields, Protein-Protein Interactions serves as a valuable resource for researchers and professionals seeking to understand the intricacies of PPIs and their significance in health and disease.